Overview
- Over 25 years of experience with a US board certified team.
- Comprehensive GLP toxicology and safety testing services.
- Highly experienced bioanalytical team, skilled in both chemistry and biology.
- Backed by Aragen’s globally integrated and operating team of over 3500 scientists.
- Access to Aragen’s full suite of discovery, development and manufacturing services.
Pharmaceutical & Biotechnology Industries
- Small molecules, vaccines, biologics
- Analytical and Bioanalytical Method Development
- Nonclinical and Clinical Bioanalysis
- Pharmacokinetics and Toxicokinetics
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IND-Enabling GLP Toxicology & Safety
- Genetic Toxicology
- Safety Pharmacology
- Repeat dose toxicology
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NDA-Enabling GLP Toxicology
- Chronic Toxicology
- Reproductive Toxicology
- Carcinogenicity
Industrial Chemical & Agrochemical Industries
- Analytical and Bioanalytical Method Development
- Nonclinical and Clinical Bioanalysis
- Genetic Toxicology
- Pharmacokinetics and Toxicology
- Reproductive Toxicology
- Aquatic and Terrestrial Ecotoxicology
- Product Composition and Characterization
- Environmental Fate and Behavior
- Residue and Metabolism Testing
In Vitro DMPK
- Physicochemical Studies
- Biodistribution
- Biopersistence
- Permeability
- Metabolism
In Vitro Toxicology
- Genotoxicity
- Cytotoxicity
- Cardiotoxicity
- Liver Toxicity
- Neurotoxicity
- Ocular Toxicity
Disease Models for Efficacy Assessment
- Infectious disease
- Oncology
- Respiratory
- Fibrosis
- Cardiovascular
- Metabolic
- Pain
- Inflammation
- Immunology
Chemistry, Manufacturing and Controls
- Synthetic chemistry
- Discovery chemistry
- Hit identification
- Lead generation & optimization
- Library design & synthesis
- Computational & analytical chemistry
- Extensive chemical toolbox
- Scale-up to support large scale synthesis
Molecular Biology
- Design of constructs and primers
- DNA, mRNA, RNA isolation
- Expression construct generation
- Plasmid isolation
Cell Line Development
- Promotors
- Selection markers
- Reporter genes
- FACS sorting
- Chemical-based transfection
- Electroporation
- Nucleofection
- Viral-based transfection
Protein Expression and Production, mg-gram
- Microbial
- Insect
- Mammalian
Protein Purification & Modification, mg-gram
- Diverse resin chemistry
- Tag cleavage
- Solubilization
- Refolding screens
- Conjugation
Protein Characterization
- Identity, quantitation, purity
- Affinity, aggregation
- Charge variant analysis
- Immunoreactivity
- Host cell proteins
- Host cell DNA
- Endotoxins
- Thermal shift
Aragen Life Sciences is a leading Contract Research, Development and Manufacturing Organization (CRDMO) offering end-to-end integrated and standalone solutions for crop protection and industrial chemical industries as well drug, vaccine and biologics developers.
Let's start your journey to safer solutions
